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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Nitric Oxide Synthase, endothelial' and Monomerid = 50081083   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nitric oxide synthase, endothelial


(Homo sapiens (Human))
BDBM50081083
PNG
(6-{4-[2-(4-Isobutyl-piperazin-1-yl)-ethyl]-phenyl}...)
Show SMILES CC(C)CN1CCN(CCc2ccc(cc2)-c2cccc(N)n2)CC1
Show InChI InChI=1S/C21H30N4/c1-17(2)16-25-14-12-24(13-15-25)11-10-18-6-8-19(9-7-18)20-4-3-5-21(22)23-20/h3-9,17H,10-16H2,1-2H3,(H2,22,23)
PDB

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 372n/an/an/an/an/an/a



Pfizer Inc. Groton

Curated by ChEMBL


Assay Description
Inhibitory activity against human endothelial nitric oxide synthase (eNOS)


Bioorg Med Chem Lett 9: 2569-72 (1999)


Article DOI: 10.1016/s0960-894x(99)00432-1
BindingDB Entry DOI: 10.7270/Q2BC3XRP
More data for this
Ligand-Target Pair