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Found 1 hit Enz. Inhib. hit(s) with Target = 'Nitric-oxide synthase, endothelial' and Monomerid = 50081586   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nitric-oxide synthase, endothelial


(Sus scrofa)
BDBM50081586
PNG
(6-Phenyl-4-piperidin-1-yl-pteridin-2-ylamine | CHE...)
Show SMILES Nc1nc(N2CCCCC2)c2nc(cnc2n1)-c1ccccc1
Show InChI InChI=1S/C17H18N6/c18-17-21-15-14(16(22-17)23-9-5-2-6-10-23)20-13(11-19-15)12-7-3-1-4-8-12/h1,3-4,7-8,11H,2,5-6,9-10H2,(H2,18,19,21,22)
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PC cid
PC sid
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Patents


Similars

Article
PubMed
n/an/a 6.20E+4n/an/an/an/an/an/a



Julius-Maximilians University Würzburg

Curated by ChEMBL


Assay Description
Inhibitory activity against Nitric oxide synthase (derived from porcine brain cerebellum)


J Med Chem 42: 4108-21 (1999)


Article DOI: 10.1021/jm981129a
BindingDB Entry DOI: 10.7270/Q27H1HSV
More data for this
Ligand-Target Pair