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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Gamma-amino-N-butyrate transaminase' and Monomerid = 50082743   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Gamma-amino-N-butyrate transaminase


(Sus scrofa)
BDBM50082743
PNG
((1R,4S)-4-Amino-cyclopent-2-enecarboxylic acid | C...)
Show SMILES N[C@H]1C[C@H](C=C1)C(O)=O
Show InChI InChI=1S/C6H9NO2/c7-5-2-1-4(3-5)6(8)9/h1-2,4-5H,3,7H2,(H,8,9)/t4-,5+/m0/s1
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PC sid
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Article
PubMed
4.00E+4n/an/an/an/an/an/an/an/a



Northwestern University

Curated by ChEMBL


Assay Description
Reversible inhibition of pig brain GABA-AT using GABA as substrate


Bioorg Med Chem 21: 903-11 (2013)


Article DOI: 10.1016/j.bmc.2012.12.009
BindingDB Entry DOI: 10.7270/Q2FX7BRM
More data for this
Ligand-Target Pair
Gamma-amino-N-butyrate transaminase


(Sus scrofa)
BDBM50082743
PNG
((1R,4S)-4-Amino-cyclopent-2-enecarboxylic acid | C...)
Show SMILES N[C@H]1C[C@H](C=C1)C(O)=O
Show InChI InChI=1S/C6H9NO2/c7-5-2-1-4(3-5)6(8)9/h1-2,4-5H,3,7H2,(H,8,9)/t4-,5+/m0/s1
PDB
MMDB

Reactome pathway

UniProtKB/SwissProt

B.MOAD
GoogleScholar
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
5.20E+4n/an/an/an/an/an/an/an/a



Northwestern University

Curated by ChEMBL


Assay Description
Compound was tested for the inhibition of Gamma-amino-N-butyrate transaminase (GABA-AT)


J Med Chem 42: 4725-8 (1999)


Article DOI: 10.1021/jm990271o
BindingDB Entry DOI: 10.7270/Q2JM28V2
More data for this
Ligand-Target Pair