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Found 5 Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 1' and Monomerid = 50084140
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50084140(4-((S)-Amino-carboxy-methyl)-3-methyl-benzoic acid...)
Affinity DataIC50:  8.00E+3nMAssay Description:Negative allosteric modulation of human mGluR1alpha expressed in syrian hamster AV-12 cells assessed as inhibition of quisqualate-induced phosphoinos...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50084140(4-((S)-Amino-carboxy-methyl)-3-methyl-benzoic acid...)
Affinity DataIC50:  8.80E+3nMAssay Description:Compound was tested for its agonist activity against Ser165 and Thr188 (Metabotropic glutamate receptor 1) receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50084140(4-((S)-Amino-carboxy-methyl)-3-methyl-benzoic acid...)
Affinity DataIC50:  1.90E+4nMAssay Description:Compound was tested for functional response of human metabotropic glutamate receptor mGluR1-alpha expressed in AV-12 cells by measuring inhibitory co...More data for this Ligand-Target Pair
In DepthDetails Article
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50084140(4-((S)-Amino-carboxy-methyl)-3-methyl-benzoic acid...)
Affinity DataIC50:  1.90E+4nMAssay Description:Compound was tested for functional response of human metabotropic glutamate receptor mGluR5a expressed in AV-12 cells by measuring inhibitory concent...More data for this Ligand-Target Pair
In DepthDetails Article
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50084140(4-((S)-Amino-carboxy-methyl)-3-methyl-benzoic acid...)
Affinity DataIC50: >3.00E+5nMAssay Description:Compound was tested for functional response of human metabotropic glutamate receptor mGluR1-alpha expressed in AV-12 cells by measuring inhibitory co...More data for this Ligand-Target Pair
In DepthDetails Article