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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '5-Lipoxygenase' and Monomerid = 50085182   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Arachidonate 5-lipoxygenase


(Homo sapiens (human))
BDBM50085182
PNG
((E)-4-{Cyclohexyl-[4-(quinolin-2-ylmethoxy)-phenyl...)
Show SMILES C\C(CCC(O)=O)=N/OC(C1CCCCC1)c1ccc(OCc2ccc3ccccc3n2)cc1
Show InChI InChI=1S/C28H32N2O4/c1-20(11-18-27(31)32)30-34-28(22-8-3-2-4-9-22)23-13-16-25(17-14-23)33-19-24-15-12-21-7-5-6-10-26(21)29-24/h5-7,10,12-17,22,28H,2-4,8-9,11,18-19H2,1H3,(H,31,32)/b30-20+
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Similars

Article
PubMed
n/an/a 17n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of calcium ionophore (A-23187)-stimulated LTB4 formation in human neutrophil assay


J Med Chem 43: 690-705 (2000)


Article DOI: 10.1021/jm9904102
BindingDB Entry DOI: 10.7270/Q2HD7WCR
More data for this
Ligand-Target Pair