BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '5-Lipoxygenase' and Monomerid = 50085186   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Arachidonate 5-lipoxygenase


(Homo sapiens (human))
BDBM50085186
PNG
(2-{[4-(Benzothiazol-2-ylmethoxy)-phenyl]-cyclohexy...)
Show SMILES C\C(=N/OC(C1CCCCC1)c1ccc(OCc2nc3ccccc3s2)cc1)C(O)=O
Show InChI InChI=1S/C24H26N2O4S/c1-16(24(27)28)26-30-23(17-7-3-2-4-8-17)18-11-13-19(14-12-18)29-15-22-25-20-9-5-6-10-21(20)31-22/h5-6,9-14,17,23H,2-4,7-8,15H2,1H3,(H,27,28)/b26-16+
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 60n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of calcium ionophore (A-23187)-stimulated LTB4 formation in human neutrophil assay


J Med Chem 43: 690-705 (2000)


Article DOI: 10.1021/jm9904102
BindingDB Entry DOI: 10.7270/Q2HD7WCR
More data for this
Ligand-Target Pair