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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '5-Lipoxygenase' and Monomerid = 50085190   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Arachidonate 5-lipoxygenase


(Homo sapiens (human))
BDBM50085190
PNG
(2-{Cyclohexyl-[4-(quinolin-2-ylmethoxy)-phenyl]-me...)
Show SMILES OC(=O)C(\Cc1ccc(O)cc1)=N\OC(C1CCCCC1)c1ccc(OCc2ccc3ccccc3n2)cc1
Show InChI InChI=1S/C32H32N2O5/c35-27-16-10-22(11-17-27)20-30(32(36)37)34-39-31(24-7-2-1-3-8-24)25-13-18-28(19-14-25)38-21-26-15-12-23-6-4-5-9-29(23)33-26/h4-6,9-19,24,31,35H,1-3,7-8,20-21H2,(H,36,37)/b34-30+
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Similars

Article
PubMed
n/an/a 43n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of calcium ionophore (A-23187)-stimulated LTB4 formation in human neutrophil assay


J Med Chem 43: 690-705 (2000)


Article DOI: 10.1021/jm9904102
BindingDB Entry DOI: 10.7270/Q2HD7WCR
More data for this
Ligand-Target Pair