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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '5-Lipoxygenase' and Monomerid = 50085211   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Arachidonate 5-lipoxygenase


(Homo sapiens (human))
BDBM50085211
PNG
(CHEMBL159909 | {1-[4-(Quinolin-2-ylmethoxy)-phenyl...)
Show SMILES CCCCC(O\N=C\C(O)=O)c1ccc(OCc2ccc3ccccc3n2)cc1
Show InChI InChI=1S/C23H24N2O4/c1-2-3-8-22(29-24-15-23(26)27)18-10-13-20(14-11-18)28-16-19-12-9-17-6-4-5-7-21(17)25-19/h4-7,9-15,22H,2-3,8,16H2,1H3,(H,26,27)/b24-15+
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Similars

Article
PubMed
n/an/a 52n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of calcium ionophore (A-23187)-stimulated LTB4 formation in human neutrophil assay


J Med Chem 43: 690-705 (2000)


Article DOI: 10.1021/jm9904102
BindingDB Entry DOI: 10.7270/Q2HD7WCR
More data for this
Ligand-Target Pair