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Found 1 hit Enz. Inhib. hit(s) with Target = 'Beta-1 Adrenergic Receptor' and Monomerid = 50089464   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Beta-1 adrenergic receptor


(Homo sapiens (human))
BDBM50089464
PNG
(CHEMBL286800 | N-{4-[2-((R)-2-Hydroxy-2-pyridin-3-...)
Show SMILES CC(=O)CCCc1nc(no1)-c1ccc(cc1)S(=O)(=O)Nc1ccc(CCNC[C@H](O)c2cccnc2)cc1
Show InChI InChI=1S/C28H31N5O5S/c1-20(34)4-2-6-27-31-28(32-38-27)22-9-13-25(14-10-22)39(36,37)33-24-11-7-21(8-12-24)15-17-30-19-26(35)23-5-3-16-29-18-23/h3,5,7-14,16,18,26,30,33,35H,2,4,6,15,17,19H2,1H3/t26-/m0/s1
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PC cid
PC sid
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Similars

Article
PubMed
n/an/a 7.00E+4n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards cloned human Beta-1 adrenergic receptor prepared from CHO cells in the presence of [125I]-iodocyanopindolol


Bioorg Med Chem Lett 10: 1427-9 (2000)


Article DOI: 10.1016/s0960-894x(00)00267-5
BindingDB Entry DOI: 10.7270/Q2833R8Z
More data for this
Ligand-Target Pair