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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Beta-3 Adrenergic Receptor' and Monomerid = 50091770   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Beta-3 adrenergic receptor


(Homo sapiens (Human))
BDBM50091770
PNG
(4-[4-(4-tert-Butyl-phenyl)-thiazol-2-yl]-N-{4-[2-(...)
Show SMILES CC(C)(C)c1ccc(cc1)-c1csc(n1)-c1ccc(cc1)S(=O)(=O)Nc1ccc(CCNC[C@H](O)c2cccnc2)cc1
Show InChI InChI=1S/C34H36N4O3S2/c1-34(2,3)28-12-8-25(9-13-28)31-23-42-33(37-31)26-10-16-30(17-11-26)43(40,41)38-29-14-6-24(7-15-29)18-20-36-22-32(39)27-5-4-19-35-21-27/h4-17,19,21,23,32,36,38-39H,18,20,22H2,1-3H3/t32-/m0/s1
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PC sid
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Similars

Article
PubMed
n/an/an/an/a 2.40n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Stimulated increase in cAMP in CHO cells expressing human beta-3 receptor


Bioorg Med Chem Lett 10: 1971-3 (2001)


Article DOI: 10.1016/s0960-894x(00)00390-5
BindingDB Entry DOI: 10.7270/Q26T0KV0
More data for this
Ligand-Target Pair