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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 1' and Monomerid = 50094187   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 1


(Homo sapiens (Human))
BDBM50094187
PNG
((+)1aR,7aR -2-[(2-Hydroxyimino-1a,2-dihydro-1H-7-o...)
Show SMILES COC(=O)[C@H](Cc1ccccc1)NC(=O)C12CC1C(N=O)c1ccccc1O2
Show InChI InChI=1S/C21H20N2O5/c1-27-19(24)16(11-13-7-3-2-4-8-13)22-20(25)21-12-15(21)18(23-26)14-9-5-6-10-17(14)28-21/h2-10,15-16,18H,11-12H2,1H3,(H,22,25)/t15?,16-,18?,21?/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.20E+3n/an/an/an/an/an/a



Novartis Pharma AG

Curated by ChEMBL


Assay Description
Inhibition of Quisqualate-Induced PI Hydrolysis measured in CHO Metabotropic glutamate receptor 1 Expressing Cells


J Med Chem 43: 4428-36 (2000)


Article DOI: 10.1021/jm0009944
BindingDB Entry DOI: 10.7270/Q2988688
More data for this
Ligand-Target Pair