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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M3' and Monomerid = 50095659   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM50095659
PNG
(2-(3,3-Difluoro-cyclopentyl)-2-hydroxy-N-[1-(6-met...)
Show SMILES Cc1cccc(CN2CCC(CC2)NC(=O)[C@@](O)([C@@H]2CCC(F)(F)C2)c2ccccc2)n1
Show InChI InChI=1S/C25H31F2N3O2/c1-18-6-5-9-22(28-18)17-30-14-11-21(12-15-30)29-23(31)25(32,19-7-3-2-4-8-19)20-10-13-24(26,27)16-20/h2-9,20-21,32H,10-17H2,1H3,(H,29,31)/t20-,25+/m1/s1
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Patents


Similars

Article
PubMed
8.90n/an/an/an/an/an/an/an/a



Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of [3H]-NMS binding to human muscarinic acetylcholine receptor M3 expressed in CHO cells


J Med Chem 43: 5017-29 (2001)


Article DOI: 10.1021/jm0003135
BindingDB Entry DOI: 10.7270/Q2HM57P7
More data for this
Ligand-Target Pair