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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M3' and Monomerid = 50095673   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM50095673
PNG
(2-Cyclopentyl-2-hydroxy-2-phenyl-N-(1-pyridin-2-yl...)
Show SMILES OC(C1CCCC1)(C(=O)NC1CCN(Cc2ccccn2)CC1)c1ccccc1
Show InChI InChI=1S/C24H31N3O2/c28-23(24(29,20-10-4-5-11-20)19-8-2-1-3-9-19)26-21-13-16-27(17-14-21)18-22-12-6-7-15-25-22/h1-3,6-9,12,15,20-21,29H,4-5,10-11,13-14,16-18H2,(H,26,28)
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PC cid
PC sid
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Similars

Article
PubMed
14n/an/an/an/an/an/an/an/a



Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of [3H]-NMS binding to human muscarinic acetylcholine receptor M3 expressed in CHO cells


J Med Chem 43: 5017-29 (2001)


Article DOI: 10.1021/jm0003135
BindingDB Entry DOI: 10.7270/Q2HM57P7
More data for this
Ligand-Target Pair