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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase SRC' and Monomerid = 50097990   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))
BDBM50097990
PNG
((R)-4-((S)-4-Amino-5-phenyl-pyrrolo[2,3-d]pyrimidi...)
Show SMILES CCOC(=O)C[C@H]1C[C@H](CN1C(=O)OC(C)(C)C)n1cc(-c2ccccc2)c2c(N)ncnc12
Show InChI InChI=1S/C25H31N5O4/c1-5-33-20(31)12-17-11-18(13-30(17)24(32)34-25(2,3)4)29-14-19(16-9-7-6-8-10-16)21-22(26)27-15-28-23(21)29/h6-10,14-15,17-18H,5,11-13H2,1-4H3,(H2,26,27,28)/t17-,18-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 5.00E+3n/an/an/an/an/an/a



Novartis Pharma Research

Curated by ChEMBL


Assay Description
Inhibition of p60 c-Src tyrosine kinase enzyme activity in liquid-phase tyrosine phosphorylation assay at 830 ng/mL


Bioorg Med Chem Lett 11: 853-6 (2001)


Article DOI: 10.1016/s0960-894x(01)00080-4
BindingDB Entry DOI: 10.7270/Q29P30XJ
More data for this
Ligand-Target Pair