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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Nitric Oxide Synthase, endothelial' and Monomerid = 50098959   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nitric oxide synthase, endothelial


(Homo sapiens (Human))
BDBM50098959
PNG
(5-Ethynyl-4,5-dihydro-thieno[2,3-c]pyridin-7-ylami...)
Show SMILES NC1=NC(Cc2ccsc12)C#C
Show InChI InChI=1S/C9H8N2S/c1-2-7-5-6-3-4-12-8(6)9(10)11-7/h1,3-4,7H,5H2,(H2,10,11)
PDB

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 80n/an/an/an/an/an/a



AstraZeneca R&D Charnwood

Curated by ChEMBL


Assay Description
Ability to inhibit the conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by e-NOS from HUVECcells


Bioorg Med Chem Lett 11: 1027-30 (2001)


Article DOI: 10.1016/s0960-894x(01)00120-2
BindingDB Entry DOI: 10.7270/Q2F76BT7
More data for this
Ligand-Target Pair