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Found 3 Enz. Inhib. hit(s) with Target = 'Beta-lactamase' and Monomerid = 50099185
TargetBeta-lactamase(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099185((2S,5R,6R)-3,3-Dimethyl-4,4,7-trioxo-6-(1-pyrrolid...)
Affinity DataIC50:  5.20E+3nMAssay Description:In vitro inhibitory concentration against AmpC enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase TEM(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099185((2S,5R,6R)-3,3-Dimethyl-4,4,7-trioxo-6-(1-pyrrolid...)
Affinity DataIC50:  7.90E+3nMAssay Description:In vitro inhibitory concentration against TEM-1 enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase type 2(Bacteroides fragilis)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099185((2S,5R,6R)-3,3-Dimethyl-4,4,7-trioxo-6-(1-pyrrolid...)
Affinity DataIC50:  2.20E+4nMAssay Description:In vitro inhibitory concentration against CCRA enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed