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Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Plasmin' and Monomerid = 50102771   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Urokinase-type plasminogen activator


(Homo sapiens (Human))
BDBM50102771
PNG
(2-(3-Fluoro-2-hydroxy-phenyl)-1H-benzoimidazole-5-...)
Show SMILES NC(=N)c1ccc2nc([nH]c2c1)-c1cccc(F)c1O
Show InChI InChI=1S/C14H11FN4O/c15-9-3-1-2-8(12(9)20)14-18-10-5-4-7(13(16)17)6-11(10)19-14/h1-6,20H,(H3,16,17)(H,18,19)
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Article
PubMed
550n/an/an/an/an/an/an/an/a



Axys Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
ComInhibition of Human Serine Protease Urokinase Plasminogen Activator (u-PA).


J Med Chem 44: 2753-71 (2001)


Article DOI: 10.1021/jm0100638
BindingDB Entry DOI: 10.7270/Q2RX9BC7
More data for this
Ligand-Target Pair
Plasminogen


(Homo sapiens (Human))
BDBM50102771
PNG
(2-(3-Fluoro-2-hydroxy-phenyl)-1H-benzoimidazole-5-...)
Show SMILES NC(=N)c1ccc2nc([nH]c2c1)-c1cccc(F)c1O
Show InChI InChI=1S/C14H11FN4O/c15-9-3-1-2-8(12(9)20)14-18-10-5-4-7(13(16)17)6-11(10)19-14/h1-6,20H,(H3,16,17)(H,18,19)
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PubMed
5.50E+3n/an/an/an/an/an/an/an/a



Axys Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Inhibition of Human Serine Protease Plasmin.


J Med Chem 44: 2753-71 (2001)


Article DOI: 10.1021/jm0100638
BindingDB Entry DOI: 10.7270/Q2RX9BC7
More data for this
Ligand-Target Pair
Tissue-type plasminogen activator


(Homo sapiens (Human))
BDBM50102771
PNG
(2-(3-Fluoro-2-hydroxy-phenyl)-1H-benzoimidazole-5-...)
Show SMILES NC(=N)c1ccc2nc([nH]c2c1)-c1cccc(F)c1O
Show InChI InChI=1S/C14H11FN4O/c15-9-3-1-2-8(12(9)20)14-18-10-5-4-7(13(16)17)6-11(10)19-14/h1-6,20H,(H3,16,17)(H,18,19)
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PubMed
1.00E+4n/an/an/an/an/an/an/an/a



Axys Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Inhibition of Human Serine Protease tissue type Plasminogen Activator (t-PA).


J Med Chem 44: 2753-71 (2001)


Article DOI: 10.1021/jm0100638
BindingDB Entry DOI: 10.7270/Q2RX9BC7
More data for this
Ligand-Target Pair