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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase YES' and Monomerid = 50103780   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase Yes


(Homo sapiens (Human))
BDBM50103780
PNG
(CHEMBL308734 | [4-{2-Acetylamino-2-[(S)-1-(3-carba...)
Show SMILES CCOP(O)(=O)c1cc(CC(NC(C)=O)C(=O)N[C@@H](C)c2ccc(OCC3CCCCC3)c(c2)C(N)=O)ccc1OCC(O)=O
Show InChI InChI=1S/C31H42N3O10P/c1-4-44-45(40,41)28-15-22(10-12-27(28)43-18-29(36)37)14-25(34-20(3)35)31(39)33-19(2)23-11-13-26(24(16-23)30(32)38)42-17-21-8-6-5-7-9-21/h10-13,15-16,19,21,25H,4-9,14,17-18H2,1-3H3,(H2,32,38)(H,33,39)(H,34,35)(H,36,37)(H,40,41)/t19-,25?/m0/s1
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Similars

Article
PubMed
n/an/a 1.56E+5n/an/an/an/an/an/a



ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibition of binding to Yes SH2 domain


Bioorg Med Chem Lett 11: 2319-23 (2001)


Article DOI: 10.1016/s0960-894x(01)00446-2
BindingDB Entry DOI: 10.7270/Q2513XHJ
More data for this
Ligand-Target Pair