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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Telomerase reverse transcriptase' and Monomerid = 50104463   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Telomerase reverse transcriptase


(Homo sapiens (Human))
BDBM50104463
PNG
(((R)-1-{12-[(2-Chloro-phenoxy)-hydroxy-phosphorylo...)
Show SMILES OP(=O)(OCCCCCCCCCCCCNC(=O)[C@@H](Cc1ccccc1)NC(=O)OCc1ccccc1)Oc1ccccc1Cl
Show InChI InChI=1S/C35H46ClN2O7P/c36-31-23-15-16-24-33(31)45-46(41,42)44-26-18-8-6-4-2-1-3-5-7-17-25-37-34(39)32(27-29-19-11-9-12-20-29)38-35(40)43-28-30-21-13-10-14-22-30/h9-16,19-24,32H,1-8,17-18,25-28H2,(H,37,39)(H,38,40)(H,41,42)/t32-/m1/s1
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Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Kyushu University

Curated by ChEMBL


Assay Description
Inhibitory activity against telomerase extracted from HCT 116 cell lines


Bioorg Med Chem Lett 11: 2581-4 (2001)


Article DOI: 10.1016/s0960-894x(01)00507-8
BindingDB Entry DOI: 10.7270/Q2XD10Z2
More data for this
Ligand-Target Pair