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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Telomerase reverse transcriptase' and Monomerid = 50104468   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Telomerase reverse transcriptase


(Homo sapiens (Human))
BDBM50104468
PNG
(CHEMBL313345 | Phosphoric acid 2-chloro-phenyl est...)
Show SMILES OP(=O)(OCCCCCCCCCCCCNC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H]1CCCN1)Oc1ccccc1Cl
Show InChI InChI=1S/C34H48ClN4O6P/c35-28-17-10-12-20-32(28)45-46(42,43)44-23-14-8-6-4-2-1-3-5-7-13-21-37-33(40)31(39-34(41)30-19-15-22-36-30)24-26-25-38-29-18-11-9-16-27(26)29/h9-12,16-18,20,25,30-31,36,38H,1-8,13-15,19,21-24H2,(H,37,40)(H,39,41)(H,42,43)/t30-,31-/m1/s1
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Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Kyushu University

Curated by ChEMBL


Assay Description
Inhibitory activity against telomerase extracted from HCT 116 cell lines


Bioorg Med Chem Lett 11: 2581-4 (2001)


Article DOI: 10.1016/s0960-894x(01)00507-8
BindingDB Entry DOI: 10.7270/Q2XD10Z2
More data for this
Ligand-Target Pair