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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Telomerase reverse transcriptase' and Monomerid = 50104472   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Telomerase reverse transcriptase


(Homo sapiens (Human))
BDBM50104472
PNG
(CHEMBL314161 | {(S)-1-[(R)-1-{12-[(2-Chloro-phenox...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)NCCCCCCCCCCCCOP(O)(=O)Oc1ccccc1Cl
Show InChI InChI=1S/C43H58ClN4O8P/c1-43(2,3)55-42(51)48-37(29-32-21-13-12-14-22-32)41(50)47-38(30-33-31-46-36-25-17-15-23-34(33)36)40(49)45-27-19-10-8-6-4-5-7-9-11-20-28-54-57(52,53)56-39-26-18-16-24-35(39)44/h12-18,21-26,31,37-38,46H,4-11,19-20,27-30H2,1-3H3,(H,45,49)(H,47,50)(H,48,51)(H,52,53)/t37-,38+/m0/s1
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PC cid
PC sid
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Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Kyushu University

Curated by ChEMBL


Assay Description
Inhibitory activity against telomerase extracted from HCT 116 cell lines


Bioorg Med Chem Lett 11: 2581-4 (2001)


Article DOI: 10.1016/s0960-894x(01)00507-8
BindingDB Entry DOI: 10.7270/Q2XD10Z2
More data for this
Ligand-Target Pair