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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Telomerase reverse transcriptase' and Monomerid = 50104489   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Telomerase reverse transcriptase


(Homo sapiens (Human))
BDBM50104489
PNG
(CHEMBL313020 | Phosphoric acid 12-[(S)-2-[(R)-2-am...)
Show SMILES N[C@H](Cc1cc2ccccc2[nH]1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCCCCCCCCCCCCOP(O)(=O)Oc1ccccc1Cl
Show InChI InChI=1S/C40H51ClN5O6P/c41-33-19-11-14-22-38(33)52-53(49,50)51-24-16-8-6-4-2-1-3-5-7-15-23-43-40(48)37(26-30-28-44-36-21-13-10-18-32(30)36)46-39(47)34(42)27-31-25-29-17-9-12-20-35(29)45-31/h9-14,17-22,25,28,34,37,44-45H,1-8,15-16,23-24,26-27,42H2,(H,43,48)(H,46,47)(H,49,50)/t34-,37+/m1/s1
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PC cid
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Similars

Article
PubMed
n/an/a 1.06E+4n/an/an/an/an/an/a



Kyushu University

Curated by ChEMBL


Assay Description
Inhibitory activity against telomerase extracted from HCT 116 cell lines


Bioorg Med Chem Lett 11: 2581-4 (2001)


Article DOI: 10.1016/s0960-894x(01)00507-8
BindingDB Entry DOI: 10.7270/Q2XD10Z2
More data for this
Ligand-Target Pair