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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Telomerase reverse transcriptase' and Monomerid = 50104493   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Telomerase reverse transcriptase


(Homo sapiens (Human))
BDBM50104493
PNG
((R)-4-tert-Butoxycarbonylamino-4-[(R)-1-{12-[(2-ch...)
Show SMILES CC(C)(C)OC(=O)N[C@H](CCC(O)=O)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)NCCCCCCCCCCCCOP(O)(=O)Oc1ccccc1Cl
Show InChI InChI=1S/C39H56ClN4O10P/c1-39(2,3)53-38(49)44-32(22-23-35(45)46)37(48)43-33(26-28-27-42-31-20-14-12-18-29(28)31)36(47)41-24-16-10-8-6-4-5-7-9-11-17-25-52-55(50,51)54-34-21-15-13-19-30(34)40/h12-15,18-21,27,32-33,42H,4-11,16-17,22-26H2,1-3H3,(H,41,47)(H,43,48)(H,44,49)(H,45,46)(H,50,51)/t32-,33-/m1/s1
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Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Kyushu University

Curated by ChEMBL


Assay Description
Inhibitory activity against telomerase extracted from HCT 116 cell lines


Bioorg Med Chem Lett 11: 2581-4 (2001)


Article DOI: 10.1016/s0960-894x(01)00507-8
BindingDB Entry DOI: 10.7270/Q2XD10Z2
More data for this
Ligand-Target Pair