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Found 2 Enz. Inhib. hit(s) with Target = 'Gonadotropin-releasing hormone receptor' and Monomerid = 50104538
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50104538(1-(2-Aza-bicyclo[2.2.2]oct-2-yl)-2-{2-(3,5-dimethy...)
Affinity DataIC50:  1nMAssay Description:Binding inhibition towards human pituitary gonadotropin-releasing hormone receptor using [125I]-buserelin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50104538(1-(2-Aza-bicyclo[2.2.2]oct-2-yl)-2-{2-(3,5-dimethy...)
Affinity DataIC50:  2.80nMAssay Description:In vitro functional antagonism via inhibition of GnRH-stimulated phosphatidylinositol (PI) hydrolysis in cloned Chinese hamster ovary (CHO) cells sta...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed