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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'C-C chemokine receptor type 5' and Monomerid = 50105513   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
C-C chemokine receptor type 5


(Homo sapiens (Human))
BDBM50105513
PNG
(1-((3S,4S)-1,4-Diphenyl-pyrrolidin-3-ylmethyl)-4-p...)
Show SMILES C([C@H]1CN(C[C@@H]1c1ccccc1)c1ccccc1)N1CCC(CC1)c1ccccc1
Show InChI InChI=1S/C28H32N2/c1-4-10-23(11-5-1)24-16-18-29(19-17-24)20-26-21-30(27-14-8-3-9-15-27)22-28(26)25-12-6-2-7-13-25/h1-15,24,26,28H,16-22H2/t26-,28+/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibitory concentration, binding towards C-C chemokine receptor type 5 using [125I]-MIP-1 alpha as radioligand expressed on CHO cells


Bioorg Med Chem Lett 11: 2741-5 (2001)


Article DOI: 10.1016/s0960-894x(01)00545-5
BindingDB Entry DOI: 10.7270/Q2F47NFC
More data for this
Ligand-Target Pair