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Found 4 Enz. Inhib. hit(s) with Target = 'Cytochrome P450 2D6' and Monomerid = 50106737
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of Wuppertal

Curated by ChEMBL
LigandPNGBDBM50106737(CHEMBL267865 | N-(4-Butyl-2-methyl-phenyl)-N'-hydr...)
Affinity DataIC50:  100nMAssay Description:Inhibition of CYP2D6 in human kidney microsomes assessed as inhibition of 20-HETE formation using 3-[2-(N,N-diethyl-N-methyl-amino)ethyl]-7-methoxy-4...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of Wuppertal

Curated by ChEMBL
LigandPNGBDBM50106737(CHEMBL267865 | N-(4-Butyl-2-methyl-phenyl)-N'-hydr...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant CYP2D6 using Luciferin-ME EGE as substrate incubated for 30 mins in presence of NADPH by luminescence based assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of Wuppertal

Curated by ChEMBL
LigandPNGBDBM50106737(CHEMBL267865 | N-(4-Butyl-2-methyl-phenyl)-N'-hydr...)
Affinity DataIC50:  8.39E+4nMAssay Description:Inhibition of recombinant human Cytochrome P450 2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of Wuppertal

Curated by ChEMBL
LigandPNGBDBM50106737(CHEMBL267865 | N-(4-Butyl-2-methyl-phenyl)-N'-hydr...)
Affinity DataIC50:  8.45E+4nMAssay Description:Concentration required to inhibit cytochrome P450 2D6.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed