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Found 1 hit Enz. Inhib. hit(s) with Target = 'Histamine N-methyltransferase' and Monomerid = 50110286   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine N-methyltransferase


(Rattus norvegicus)
BDBM50110286
PNG
((3-Piperidin-1-yl-propyl)-(1,2,3,4-tetrahydro-acri...)
Show SMILES C(CNc1c2CCCCc2nc2ccccc12)CN1CCCCC1
Show InChI InChI=1S/C21H29N3/c1-6-14-24(15-7-1)16-8-13-22-21-17-9-2-4-11-19(17)23-20-12-5-3-10-18(20)21/h2,4,9,11H,1,3,5-8,10,12-16H2,(H,22,23)
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 45n/an/an/an/an/an/a



Freie Universität Berlin

Curated by ChEMBL


Assay Description
Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methylhistamine


J Med Chem 45: 1128-41 (2002)


Article DOI: 10.1021/jm0110845
BindingDB Entry DOI: 10.7270/Q2H70F4V
More data for this
Ligand-Target Pair