BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histamine N-methyltransferase' and Monomerid = 50110294   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine N-methyltransferase


(Rattus norvegicus)
BDBM50110294
PNG
((5-Piperidin-1-yl-pentyl)-quinolin-4-yl-amine; Oxa...)
Show SMILES C(CCNc1ccnc2ccccc12)CCN1CCCCC1
Show InChI InChI=1S/C19H27N3/c1(6-14-22-15-7-2-8-16-22)5-12-20-19-11-13-21-18-10-4-3-9-17(18)19/h3-4,9-11,13H,1-2,5-8,12,14-16H2,(H,20,21)
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 53n/an/an/an/an/an/a



Freie Universität Berlin

Curated by ChEMBL


Assay Description
Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methylhistamine


J Med Chem 45: 1128-41 (2002)


Article DOI: 10.1021/jm0110845
BindingDB Entry DOI: 10.7270/Q2H70F4V
More data for this
Ligand-Target Pair