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Found 1 hit Enz. Inhib. hit(s) with Target = 'Histamine N-methyltransferase' and Monomerid = 50110303   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine N-methyltransferase


(Rattus norvegicus)
BDBM50110303
PNG
((2-Piperidin-1-yl-ethyl)-(1,2,3,4-tetrahydro-acrid...)
Show SMILES C(CN1CCCCC1)Nc1c2CCCCc2nc2ccccc12
Show InChI InChI=1S/C20H27N3/c1-6-13-23(14-7-1)15-12-21-20-16-8-2-4-10-18(16)22-19-11-5-3-9-17(19)20/h2,4,8,10H,1,3,5-7,9,11-15H2,(H,21,22)
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 34n/an/an/an/an/an/a



Freie Universität Berlin

Curated by ChEMBL


Assay Description
Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methylhistamine


J Med Chem 45: 1128-41 (2002)


Article DOI: 10.1021/jm0110845
BindingDB Entry DOI: 10.7270/Q2H70F4V
More data for this
Ligand-Target Pair