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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M2' and Monomerid = 50111325   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))
BDBM50111325
PNG
((2-Fluoro-phenyl)-[4-(4-isopropylsulfanyl-benzyl)-...)
Show SMILES CC(C)Sc1ccc(CC2CCN(CC2)C2CCN(CC2)C(=O)c2ccccc2F)cc1
Show InChI InChI=1S/C27H35FN2OS/c1-20(2)32-24-9-7-21(8-10-24)19-22-11-15-29(16-12-22)23-13-17-30(18-14-23)27(31)25-5-3-4-6-26(25)28/h3-10,20,22-23H,11-19H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
260n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Binding affinity against muscarinic acetylcholine receptor M2 stably expressed in CHO-K1 cells using [3H]-QNB as radioligand.


Bioorg Med Chem Lett 12: 1087-91 (2002)


Article DOI: 10.1016/s0960-894x(02)00096-3
BindingDB Entry DOI: 10.7270/Q2MS3S2P
More data for this
Ligand-Target Pair