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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase SRC' and Monomerid = 50112421   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))
BDBM50112421
PNG
(CHEMBL286258 | Phosphoric acid mono-(4-{2-acetylam...)
Show SMILES CC(=O)N[C@@H](Cc1ccc(OP(O)(O)=O)cc1)C(=O)N[C@H]1CCCCN(CCCc2ccccc2)C1=O
Show InChI InChI=1S/C26H34N3O7P/c1-19(30)27-24(18-21-12-14-22(15-13-21)36-37(33,34)35)25(31)28-23-11-5-6-16-29(26(23)32)17-7-10-20-8-3-2-4-9-20/h2-4,8-9,12-15,23-24H,5-7,10-11,16-18H2,1H3,(H,27,30)(H,28,31)(H2,33,34,35)/t23-,24-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 290n/an/an/an/an/an/a



Aventis Pharma

Curated by ChEMBL


Assay Description
Inhibitory concentration against SH2 domain of human p60 Src tyrosine kinase


J Med Chem 45: 2915-22 (2002)


Article DOI: 10.1021/jm0110800
BindingDB Entry DOI: 10.7270/Q2ZW1MNM
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))
BDBM50112421
PNG
(CHEMBL286258 | Phosphoric acid mono-(4-{2-acetylam...)
Show SMILES CC(=O)N[C@@H](Cc1ccc(OP(O)(O)=O)cc1)C(=O)N[C@H]1CCCCN(CCCc2ccccc2)C1=O
Show InChI InChI=1S/C26H34N3O7P/c1-19(30)27-24(18-21-12-14-22(15-13-21)36-37(33,34)35)25(31)28-23-11-5-6-16-29(26(23)32)17-7-10-20-8-3-2-4-9-20/h2-4,8-9,12-15,23-24H,5-7,10-11,16-18H2,1H3,(H,27,30)(H,28,31)(H2,33,34,35)/t23-,24-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 290n/an/an/an/an/an/a



Aventis Pharma

Curated by ChEMBL


Assay Description
Binding affinity towards p60 Src tyrosine kinase using scintillation proximity assay


Bioorg Med Chem Lett 12: 1291-4 (2002)


Article DOI: 10.1016/s0960-894x(02)00139-7
BindingDB Entry DOI: 10.7270/Q2DZ07MZ
More data for this
Ligand-Target Pair