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Found 1 hit Enz. Inhib. hit(s) with Target = 'Nitric Oxide Synthase, brain' and Monomerid = 50113344   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nitric oxide synthase, brain


(Homo sapiens (Human))
BDBM50113344
PNG
(2-[1,2]Dithiolan-3-yl-N-(2-{4-[(thiophene-2-carbox...)
Show SMILES NC(=Nc1ccc(CCNC(=O)CC2CCSS2)cc1)c1cccs1
Show InChI InChI=1/C18H21N3OS3/c19-18(16-2-1-10-23-16)21-14-5-3-13(4-6-14)7-9-20-17(22)12-15-8-11-24-25-15/h1-6,10,15H,7-9,11-12H2,(H2,19,21)(H,20,22)
PDB
MMDB

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Similars

Article
PubMed
n/an/a 1.15E+3n/an/an/an/an/an/a



Institute Henri Beaufour

Curated by ChEMBL


Assay Description
In vitro inhibition concentration of the compound was evaluated on the effect of conversion by Nitric Oxide synthase of [3H]-L-arginine into [3H]-L-c...


Bioorg Med Chem Lett 12: 1439-42 (2002)


Article DOI: 10.1016/s0960-894x(02)00216-0
BindingDB Entry DOI: 10.7270/Q26972WQ
More data for this
Ligand-Target Pair