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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase LCK' and Monomerid = 50114582   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase Lck


(Homo sapiens (Human))
BDBM50114582
PNG
(7-Isoxazolidin-4-yl-5-(4-phenoxy-phenyl)-7H-pyrrol...)
Show SMILES Nc1ncnc2n(cc(-c3ccc(Oc4ccccc4)cc3)c12)C1CNOC1
Show InChI InChI=1/C21H19N5O2/c22-20-19-18(11-26(15-10-25-27-12-15)21(19)24-13-23-20)14-6-8-17(9-7-14)28-16-4-2-1-3-5-16/h1-9,11,13,15,25H,10,12H2,(H2,22,23,24)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 46n/an/an/an/an/an/a



Abbott Bioresearch Center

Curated by ChEMBL


Assay Description
Inhibition of human p56 Lck tyrosine kinase (lck64-509)


Bioorg Med Chem Lett 12: 1683-6 (2002)


Article DOI: 10.1016/s0960-894x(02)00195-6
BindingDB Entry DOI: 10.7270/Q23B5ZGR
More data for this
Ligand-Target Pair