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Found 1 hit Enz. Inhib. hit(s) with Target = 'Nitric Oxide Synthase, brain' and Monomerid = 50115157   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nitric oxide synthase, brain


(Homo sapiens (Human))
BDBM50115157
PNG
(CHEMBL101513 | N*4*,N*4*-Dimethyl-6-p-tolyl-pterid...)
Show SMILES CN(C)c1nc(N)nc2ncc(nc12)-c1ccc(C)cc1
Show InChI InChI=1S/C15H16N6/c1-9-4-6-10(7-5-9)11-8-17-13-12(18-11)14(21(2)3)20-15(16)19-13/h4-8H,1-3H3,(H2,16,17,19,20)
PDB
MMDB

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PC cid
PC sid
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Patents


Similars

Article
PubMed
n/an/a 7.50E+4n/an/an/an/an/an/a



Aventis Pharma

Curated by ChEMBL


Assay Description
Inhibitory activity against human neuronal nitric oxide synthase (NOS-I)


J Med Chem 45: 2923-41 (2002)


Article DOI: 10.1021/jm020074g
BindingDB Entry DOI: 10.7270/Q2571BBK
More data for this
Ligand-Target Pair