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Found 1 hit Enz. Inhib. hit(s) with Target = 'Nitric Oxide Synthase, brain' and Monomerid = 50115165   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nitric oxide synthase, brain


(Homo sapiens (Human))
BDBM50115165
PNG
(4-Pentyloxy-6-phenylethynyl-pteridin-2-ylamine | C...)
Show SMILES CCCCCOc1nc(N)nc2ncc(nc12)C#Cc1ccccc1
Show InChI InChI=1S/C19H19N5O/c1-2-3-7-12-25-18-16-17(23-19(20)24-18)21-13-15(22-16)11-10-14-8-5-4-6-9-14/h4-6,8-9,13H,2-3,7,12H2,1H3,(H2,20,21,23,24)
PDB
MMDB

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B.MOAD
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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 8.00E+3n/an/an/an/an/an/a



Aventis Pharma

Curated by ChEMBL


Assay Description
Inhibitory activity against human neuronal nitric oxide synthase (NOS-I)


J Med Chem 45: 2923-41 (2002)


Article DOI: 10.1021/jm020074g
BindingDB Entry DOI: 10.7270/Q2571BBK
More data for this
Ligand-Target Pair