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Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Plasmin' and Monomerid = 50115891   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Urokinase-type plasminogen activator


(Homo sapiens (Human))
BDBM50115891
PNG
(3-Hydroxy-anthracene-2-carboxylic acid (4-guanidin...)
Show SMILES NC(N)=Nc1ccc(NC(=O)c2cc3cc4ccccc4cc3cc2O)cc1
Show InChI InChI=1S/C22H18N4O2/c23-22(24)26-18-7-5-17(6-8-18)25-21(28)19-11-15-9-13-3-1-2-4-14(13)10-16(15)12-20(19)27/h1-12,27H,(H,25,28)(H4,23,24,26)
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300n/an/an/an/an/an/an/an/a



Celera

Curated by ChEMBL


Assay Description
Inhibition of urokinase-type plasminogen activator (microPa)


Bioorg Med Chem Lett 12: 2023-6 (2002)


Article DOI: 10.1016/s0960-894x(02)00312-8
BindingDB Entry DOI: 10.7270/Q2ZG6RK4
More data for this
Ligand-Target Pair
Tissue-type plasminogen activator


(Homo sapiens (Human))
BDBM50115891
PNG
(3-Hydroxy-anthracene-2-carboxylic acid (4-guanidin...)
Show SMILES NC(N)=Nc1ccc(NC(=O)c2cc3cc4ccccc4cc3cc2O)cc1
Show InChI InChI=1S/C22H18N4O2/c23-22(24)26-18-7-5-17(6-8-18)25-21(28)19-11-15-9-13-3-1-2-4-14(13)10-16(15)12-20(19)27/h1-12,27H,(H,25,28)(H4,23,24,26)
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PubMed
>9.50E+4n/an/an/an/an/an/an/an/a



Celera

Curated by ChEMBL


Assay Description
Activation of tissue plasminogen


Bioorg Med Chem Lett 12: 2023-6 (2002)


Article DOI: 10.1016/s0960-894x(02)00312-8
BindingDB Entry DOI: 10.7270/Q2ZG6RK4
More data for this
Ligand-Target Pair
Plasminogen


(Homo sapiens (Human))
BDBM50115891
PNG
(3-Hydroxy-anthracene-2-carboxylic acid (4-guanidin...)
Show SMILES NC(N)=Nc1ccc(NC(=O)c2cc3cc4ccccc4cc3cc2O)cc1
Show InChI InChI=1S/C22H18N4O2/c23-22(24)26-18-7-5-17(6-8-18)25-21(28)19-11-15-9-13-3-1-2-4-14(13)10-16(15)12-20(19)27/h1-12,27H,(H,25,28)(H4,23,24,26)
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PubMed
2.83E+5n/an/an/an/an/an/an/an/a



Celera

Curated by ChEMBL


Assay Description
Inhibition of plasmin


Bioorg Med Chem Lett 12: 2023-6 (2002)


Article DOI: 10.1016/s0960-894x(02)00312-8
BindingDB Entry DOI: 10.7270/Q2ZG6RK4
More data for this
Ligand-Target Pair