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Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Plasmin' and Monomerid = 50115897   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Urokinase-type plasminogen activator


(Homo sapiens (Human))
BDBM50115897
PNG
(CHEMBL64841 | N-(4-Guanidino-phenyl)-2-hydroxy-5-m...)
Show SMILES Cc1ccc(O)c(c1)C(=O)Nc1ccc(cc1)N=C(N)N
Show InChI InChI=1S/C15H16N4O2/c1-9-2-7-13(20)12(8-9)14(21)18-10-3-5-11(6-4-10)19-15(16)17/h2-8,20H,1H3,(H,18,21)(H4,16,17,19)
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Article
PubMed
1.30E+4n/an/an/an/an/an/an/an/a



Celera

Curated by ChEMBL


Assay Description
Inhibition of urokinase-type plasminogen activator (microPa)


Bioorg Med Chem Lett 12: 2023-6 (2002)


Article DOI: 10.1016/s0960-894x(02)00312-8
BindingDB Entry DOI: 10.7270/Q2ZG6RK4
More data for this
Ligand-Target Pair
Plasminogen


(Homo sapiens (Human))
BDBM50115897
PNG
(CHEMBL64841 | N-(4-Guanidino-phenyl)-2-hydroxy-5-m...)
Show SMILES Cc1ccc(O)c(c1)C(=O)Nc1ccc(cc1)N=C(N)N
Show InChI InChI=1S/C15H16N4O2/c1-9-2-7-13(20)12(8-9)14(21)18-10-3-5-11(6-4-10)19-15(16)17/h2-8,20H,1H3,(H,18,21)(H4,16,17,19)
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Article
PubMed
>7.50E+4n/an/an/an/an/an/an/an/a



Celera

Curated by ChEMBL


Assay Description
Inhibition of plasmin


Bioorg Med Chem Lett 12: 2023-6 (2002)


Article DOI: 10.1016/s0960-894x(02)00312-8
BindingDB Entry DOI: 10.7270/Q2ZG6RK4
More data for this
Ligand-Target Pair
Tissue-type plasminogen activator


(Homo sapiens (Human))
BDBM50115897
PNG
(CHEMBL64841 | N-(4-Guanidino-phenyl)-2-hydroxy-5-m...)
Show SMILES Cc1ccc(O)c(c1)C(=O)Nc1ccc(cc1)N=C(N)N
Show InChI InChI=1S/C15H16N4O2/c1-9-2-7-13(20)12(8-9)14(21)18-10-3-5-11(6-4-10)19-15(16)17/h2-8,20H,1H3,(H,18,21)(H4,16,17,19)
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UniChem

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Article
PubMed
>9.50E+4n/an/an/an/an/an/an/an/a



Celera

Curated by ChEMBL


Assay Description
Activation of plasminogen


Bioorg Med Chem Lett 12: 2023-6 (2002)


Article DOI: 10.1016/s0960-894x(02)00312-8
BindingDB Entry DOI: 10.7270/Q2ZG6RK4
More data for this
Ligand-Target Pair