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Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Plasmin' and Monomerid = 50115905   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Urokinase-type plasminogen activator


(Homo sapiens (Human))
BDBM50115905
PNG
(3-Hydroxy-4-methoxy-anthracene-2-carboxylic acid (...)
Show SMILES COc1c(O)c(cc2cc3ccccc3cc12)C(=O)Nc1ccc(N=C(N)N)nc1
Show InChI InChI=1S/C22H19N5O3/c1-30-20-16-9-13-5-3-2-4-12(13)8-14(16)10-17(19(20)28)21(29)26-15-6-7-18(25-11-15)27-22(23)24/h2-11,28H,1H3,(H,26,29)(H4,23,24,25,27)
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280n/an/an/an/an/an/an/an/a



Celera

Curated by ChEMBL


Assay Description
Inhibition of urokinase-type plasminogen activator (microPa)


Bioorg Med Chem Lett 12: 2023-6 (2002)


Article DOI: 10.1016/s0960-894x(02)00312-8
BindingDB Entry DOI: 10.7270/Q2ZG6RK4
More data for this
Ligand-Target Pair
Plasminogen


(Homo sapiens (Human))
BDBM50115905
PNG
(3-Hydroxy-4-methoxy-anthracene-2-carboxylic acid (...)
Show SMILES COc1c(O)c(cc2cc3ccccc3cc12)C(=O)Nc1ccc(N=C(N)N)nc1
Show InChI InChI=1S/C22H19N5O3/c1-30-20-16-9-13-5-3-2-4-12(13)8-14(16)10-17(19(20)28)21(29)26-15-6-7-18(25-11-15)27-22(23)24/h2-11,28H,1H3,(H,26,29)(H4,23,24,25,27)
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>7.50E+4n/an/an/an/an/an/an/an/a



Celera

Curated by ChEMBL


Assay Description
Inhibition of plasmin


Bioorg Med Chem Lett 12: 2023-6 (2002)


Article DOI: 10.1016/s0960-894x(02)00312-8
BindingDB Entry DOI: 10.7270/Q2ZG6RK4
More data for this
Ligand-Target Pair
Tissue-type plasminogen activator


(Homo sapiens (Human))
BDBM50115905
PNG
(3-Hydroxy-4-methoxy-anthracene-2-carboxylic acid (...)
Show SMILES COc1c(O)c(cc2cc3ccccc3cc12)C(=O)Nc1ccc(N=C(N)N)nc1
Show InChI InChI=1S/C22H19N5O3/c1-30-20-16-9-13-5-3-2-4-12(13)8-14(16)10-17(19(20)28)21(29)26-15-6-7-18(25-11-15)27-22(23)24/h2-11,28H,1H3,(H,26,29)(H4,23,24,25,27)
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PubMed
1.50E+5n/an/an/an/an/an/an/an/a



Celera

Curated by ChEMBL


Assay Description
Activation of tissue plasminogen


Bioorg Med Chem Lett 12: 2023-6 (2002)


Article DOI: 10.1016/s0960-894x(02)00312-8
BindingDB Entry DOI: 10.7270/Q2ZG6RK4
More data for this
Ligand-Target Pair