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Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Progesterone receptor' and Monomerid = 50118700   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Progesterone receptor


(Homo sapiens (Human))
BDBM50118700
PNG
(6-(3-Chloro-phenyl)-4,4-dimethyl-1,4-dihydro-benzo...)
Show SMILES CC1(C)OC(=O)Nc2ccc(cc12)-c1cccc(Cl)c1
Show InChI InChI=1S/C16H14ClNO2/c1-16(2)13-9-11(10-4-3-5-12(17)8-10)6-7-14(13)18-15(19)20-16/h3-9H,1-2H3,(H,18,19)
PDB

KEGG

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

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Similars

Article
PubMed
n/an/a 9.30n/an/an/an/an/an/a



Women's Health Research Institute

Curated by ChEMBL


Assay Description
Antagonist activity against progesterone receptor (PR) in an assay using PRE-luciferase plasmid co-transfected CV-1 cells


J Med Chem 45: 4379-82 (2002)


Article DOI: 10.1021/jm025555e
BindingDB Entry DOI: 10.7270/Q22F7P5W
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50118700
PNG
(6-(3-Chloro-phenyl)-4,4-dimethyl-1,4-dihydro-benzo...)
Show SMILES CC1(C)OC(=O)Nc2ccc(cc12)-c1cccc(Cl)c1
Show InChI InChI=1S/C16H14ClNO2/c1-16(2)13-9-11(10-4-3-5-12(17)8-10)6-7-14(13)18-15(19)20-16/h3-9H,1-2H3,(H,18,19)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 30n/an/an/an/an/an/a



Women's Health Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human progesterone receptor


J Med Chem 48: 5092-5 (2005)


Article DOI: 10.1021/jm050358b
BindingDB Entry DOI: 10.7270/Q2FF3RXG
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50118700
PNG
(6-(3-Chloro-phenyl)-4,4-dimethyl-1,4-dihydro-benzo...)
Show SMILES CC1(C)OC(=O)Nc2ccc(cc12)-c1cccc(Cl)c1
Show InChI InChI=1S/C16H14ClNO2/c1-16(2)13-9-11(10-4-3-5-12(17)8-10)6-7-14(13)18-15(19)20-16/h3-9H,1-2H3,(H,18,19)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 30n/an/an/an/an/an/a



Women's Health Research Institute

Curated by ChEMBL


Assay Description
Antagonist activity against progesterone receptor (PR) in an alkaline phosphatase assay in the T47D human breast carcinoma cell line


J Med Chem 45: 4379-82 (2002)


Article DOI: 10.1021/jm025555e
BindingDB Entry DOI: 10.7270/Q22F7P5W
More data for this
Ligand-Target Pair