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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Beta-1 Adrenergic Receptor' and Monomerid = 50119173   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Beta-1 adrenergic receptor


(Homo sapiens (human))
BDBM50119173
PNG
(1-(2,5-Difluoro-benzyl)-3-[4-(4-{[(S)-2-hydroxy-3-...)
Show SMILES O[C@@H](CNCC1CCN(CC1)S(=O)(=O)c1ccc(NC(=O)NCc2cc(F)ccc2F)cc1)COc1ccc(O)cc1
Show InChI InChI=1S/C29H34F2N4O6S/c30-22-1-10-28(31)21(15-22)17-33-29(38)34-23-2-8-27(9-3-23)42(39,40)35-13-11-20(12-14-35)16-32-18-25(37)19-41-26-6-4-24(36)5-7-26/h1-10,15,20,25,32,36-37H,11-14,16-19H2,(H2,33,34,38)/t25-/m0/s1
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Patents


Similars

Article
PubMed
n/an/an/an/a 1.01E+3n/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
In vitro agonist activity measured by increase in cAMP levels in chinese hamster ovary cells (CHO) cells expressing human Beta-1 adrenergic receptor


Bioorg Med Chem Lett 12: 2957-61 (2002)


Article DOI: 10.1016/s0960-894x(02)00607-8
BindingDB Entry DOI: 10.7270/Q2HT2NP4
More data for this
Ligand-Target Pair