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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Beta-1 Adrenergic Receptor' and Monomerid = 50119200   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Beta-1 adrenergic receptor


(Homo sapiens (Human))
BDBM50119200
PNG
(4-Aminomethylpiperidine substituted analogue | CHE...)
Show SMILES CC(C)C[C@H](NC(=O)c1ccc(cc1)N1CCC(CNC[C@H](O)c2ccc(O)c(NS(C)(=O)=O)c2)CC1)C(O)=O
Show InChI InChI=1S/C28H40N4O7S/c1-18(2)14-24(28(36)37)30-27(35)20-4-7-22(8-5-20)32-12-10-19(11-13-32)16-29-17-26(34)21-6-9-25(33)23(15-21)31-40(3,38)39/h4-9,15,18-19,24,26,29,31,33-34H,10-14,16-17H2,1-3H3,(H,30,35)(H,36,37)/t24-,26-/m0/s1
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PC sid
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Patents


Similars

Article
PubMed
n/an/an/an/a 1.86E+3n/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Beta-1 adrenergic receptor agonist activity as increased cAMP levels in CHO cells expressing human Beta1-adrenoreceptor


Bioorg Med Chem Lett 12: 2963-7 (2002)


Article DOI: 10.1016/s0960-894x(02)00608-x
BindingDB Entry DOI: 10.7270/Q2D21WZQ
More data for this
Ligand-Target Pair