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Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Retinoid X receptor gamma' and Monomerid = 50122348   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Retinoid X receptor gamma/retinoic acid receptor alpha


(Homo sapiens (Human))
BDBM50122348
PNG
((2E,4E)-6-[1-(3,5-Di-tert-butyl-phenyl)-cyclopropy...)
Show SMILES C\C(\C=C\CC1(CC1)c1cc(cc(c1)C(C)(C)C)C(C)(C)C)=C/C(O)=O
Show InChI InChI=1S/C24H34O2/c1-17(13-21(25)26)9-8-10-24(11-12-24)20-15-18(22(2,3)4)14-19(16-20)23(5,6)7/h8-9,13-16H,10-12H2,1-7H3,(H,25,26)/b9-8+,17-13+
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PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 733n/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Transcriptional activation in CV-1 cells expresing human Retinoic acid receptor RAR alpha


Bioorg Med Chem Lett 13: 261-4 (2002)


Article DOI: 10.1016/s0960-894x(02)00924-1
BindingDB Entry DOI: 10.7270/Q29P310V
More data for this
Ligand-Target Pair
Retinoid X receptor gamma/retinoic acid receptor alpha


(Homo sapiens (Human))
BDBM50122348
PNG
((2E,4E)-6-[1-(3,5-Di-tert-butyl-phenyl)-cyclopropy...)
Show SMILES C\C(\C=C\CC1(CC1)c1cc(cc(c1)C(C)(C)C)C(C)(C)C)=C/C(O)=O
Show InChI InChI=1S/C24H34O2/c1-17(13-21(25)26)9-8-10-24(11-12-24)20-15-18(22(2,3)4)14-19(16-20)23(5,6)7/h8-9,13-16H,10-12H2,1-7H3,(H,25,26)/b9-8+,17-13+
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PC cid
PC sid
UniChem
Article
PubMed
n/an/an/a 16n/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibition of [3H]-9-cis-RA binding to human Retinoid X receptor RXR gamma


Bioorg Med Chem Lett 13: 261-4 (2002)


Article DOI: 10.1016/s0960-894x(02)00924-1
BindingDB Entry DOI: 10.7270/Q29P310V
More data for this
Ligand-Target Pair
Retinoid X receptor gamma


(Mus musculus)
BDBM50122348
PNG
((2E,4E)-6-[1-(3,5-Di-tert-butyl-phenyl)-cyclopropy...)
Show SMILES C\C(\C=C\CC1(CC1)c1cc(cc(c1)C(C)(C)C)C(C)(C)C)=C/C(O)=O
Show InChI InChI=1S/C24H34O2/c1-17(13-21(25)26)9-8-10-24(11-12-24)20-15-18(22(2,3)4)14-19(16-20)23(5,6)7/h8-9,13-16H,10-12H2,1-7H3,(H,25,26)/b9-8+,17-13+
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 23n/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Transcriptional activation in CV-1 cells expresing mouse Retinoid X receptor RXR gamma


Bioorg Med Chem Lett 13: 261-4 (2002)


Article DOI: 10.1016/s0960-894x(02)00924-1
BindingDB Entry DOI: 10.7270/Q29P310V
More data for this
Ligand-Target Pair