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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Nitric Oxide Synthase, endothelial' and Monomerid = 50124528   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nitric oxide synthase, endothelial


(Homo sapiens (Human))
BDBM50124528
PNG
(CHEMBL170176 | ethyl 4'-amino-1H,1'H-spiro[piperid...)
Show SMILES CCOC(=O)N1CCC2(CC1)Nc1ccsc1C(N)=N2
Show InChI InChI=1S/C13H18N4O2S/c1-2-19-12(18)17-6-4-13(5-7-17)15-9-3-8-20-10(9)11(14)16-13/h3,8,15H,2,4-7H2,1H3,(H2,14,16)
PDB

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.00E+5n/an/an/an/an/an/a



AstraZeneca R& D Charnwood

Curated by ChEMBL


Assay Description
Inhibitory activity against human endothelial nitiric oxide synthase


J Med Chem 46: 913-6 (2003)


Article DOI: 10.1021/jm0255926
BindingDB Entry DOI: 10.7270/Q2S75H3M
More data for this
Ligand-Target Pair