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Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Peroxisome proliferator-activated receptor delta' and Monomerid = 50126017   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Peroxisome proliferator-activated receptor delta


(Homo sapiens (Human))
BDBM50126017
PNG
(CHEMBL23670 | {3-Chloro-4-[3-(3-ethyl-7-propyl-ben...)
Show SMILES CCCc1c(OCCCSc2ccc(CC(O)=O)cc2Cl)ccc2c(CC)coc12
Show InChI InChI=1S/C24H27ClO4S/c1-3-6-19-21(9-8-18-17(4-2)15-29-24(18)19)28-11-5-12-30-22-10-7-16(13-20(22)25)14-23(26)27/h7-10,13,15H,3-6,11-12,14H2,1-2H3,(H,26,27)
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Article
PubMed
n/an/a 40.0n/an/an/an/an/an/a



Universidad Nacional Aut£noma de M£xico

Curated by ChEMBL


Assay Description
Agonist activity at PPARdelta


Bioorg Med Chem 20: 3523-32 (2012)


Article DOI: 10.1016/j.bmc.2012.04.005
BindingDB Entry DOI: 10.7270/Q2MP54B4
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta


(Homo sapiens (Human))
BDBM50126017
PNG
(CHEMBL23670 | {3-Chloro-4-[3-(3-ethyl-7-propyl-ben...)
Show SMILES CCCc1c(OCCCSc2ccc(CC(O)=O)cc2Cl)ccc2c(CC)coc12
Show InChI InChI=1S/C24H27ClO4S/c1-3-6-19-21(9-8-18-17(4-2)15-29-24(18)19)28-11-5-12-30-22-10-7-16(13-20(22)25)14-23(26)27/h7-10,13,15H,3-6,11-12,14H2,1-2H3,(H,26,27)
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Article
PubMed
n/an/a 40n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity for human PPAR delta in SPA


Bioorg Med Chem Lett 13: 1277-80 (2003)


Article DOI: 10.1016/s0960-894x(03)00115-x
BindingDB Entry DOI: 10.7270/Q2PC31R1
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta


(Homo sapiens (Human))
BDBM50126017
PNG
(CHEMBL23670 | {3-Chloro-4-[3-(3-ethyl-7-propyl-ben...)
Show SMILES CCCc1c(OCCCSc2ccc(CC(O)=O)cc2Cl)ccc2c(CC)coc12
Show InChI InChI=1S/C24H27ClO4S/c1-3-6-19-21(9-8-18-17(4-2)15-29-24(18)19)28-11-5-12-30-22-10-7-16(13-20(22)25)14-23(26)27/h7-10,13,15H,3-6,11-12,14H2,1-2H3,(H,26,27)
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Article
PubMed
n/an/a 40n/an/an/an/an/an/a



Universidad Nacional Aut£noma de M£xico

Curated by ChEMBL


Assay Description
Agonist activity at PPARdelta


Bioorg Med Chem 20: 3523-32 (2012)


Article DOI: 10.1016/j.bmc.2012.04.005
BindingDB Entry DOI: 10.7270/Q2MP54B4
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta


(Homo sapiens (Human))
BDBM50126017
PNG
(CHEMBL23670 | {3-Chloro-4-[3-(3-ethyl-7-propyl-ben...)
Show SMILES CCCc1c(OCCCSc2ccc(CC(O)=O)cc2Cl)ccc2c(CC)coc12
Show InChI InChI=1S/C24H27ClO4S/c1-3-6-19-21(9-8-18-17(4-2)15-29-24(18)19)28-11-5-12-30-22-10-7-16(13-20(22)25)14-23(26)27/h7-10,13,15H,3-6,11-12,14H2,1-2H3,(H,26,27)
PDB

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PC cid
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Article
PubMed
n/an/an/an/a 12n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Transcriptional activation by human PPAR alpha


Bioorg Med Chem Lett 13: 1277-80 (2003)


Article DOI: 10.1016/s0960-894x(03)00115-x
BindingDB Entry DOI: 10.7270/Q2PC31R1
More data for this
Ligand-Target Pair