BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Nitric Oxide Synthase, inducible' and Monomerid = 50127039   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nitric Oxide Synthase, inducible


(Mus musculus (mouse)-Homo sapiens (Human))
BDBM50127039
PNG
(CHEMBL297207 | N-((4S)-4-amino-5-{[2-(aminomethyl)...)
Show SMILES NCc1ccccc1NC[C@@H](N)CCCNC(=N)N[N+]([O-])=O
Show InChI InChI=1S/C13H23N7O2/c14-8-10-4-1-2-6-12(10)18-9-11(15)5-3-7-17-13(16)19-20(21)22/h1-2,4,6,11,18H,3,5,7-9,14-15H2,(H3,16,17,19)/t11-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
2.93E+4n/an/an/an/an/an/an/an/a



Northwestern University

Curated by ChEMBL


Assay Description
Inhibitory activity against Inducible nitric oxide synthase


J Med Chem 46: 5700-11 (2003)

Checked by Author
Article DOI: 10.1021/jm030301u
BindingDB Entry DOI: 10.7270/Q26D5TQV
More data for this
Ligand-Target Pair
Nitric Oxide Synthase, inducible


(Mus musculus (mouse))
BDBM50127039
PNG
(CHEMBL297207 | N-((4S)-4-amino-5-{[2-(aminomethyl)...)
Show SMILES NCc1ccccc1NC[C@@H](N)CCCNC(=N)N[N+]([O-])=O
Show InChI InChI=1S/C13H23N7O2/c14-8-10-4-1-2-6-12(10)18-9-11(15)5-3-7-17-13(16)19-20(21)22/h1-2,4,6,11,18H,3,5,7-9,14-15H2,(H3,16,17,19)/t11-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
2.93E+4n/an/an/an/an/an/an/an/a



Northwestern University

Curated by ChEMBL


Assay Description
Inhibitory activity against Inducible nitric oxide synthase (iNOS)


J Med Chem 46: 1661-9 (2003)


Article DOI: 10.1021/jm0202932
BindingDB Entry DOI: 10.7270/Q23J3DQK
More data for this
Ligand-Target Pair