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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase SRC' and Monomerid = 50128844   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase SRC


(Rattus norvegicus)
BDBM50128844
PNG
(2-(16-Chloro-17,19-dihydroxy-4-methyl-2-oxo-3,7-di...)
Show SMILES C[C@@H]1C[C@H]2O[C@@H]2\C=C/C=C/C(/Cc2c(Cl)c(O)cc(O)c2C(=O)O1)=N\OCC(=O)NCCO
Show InChI InChI=1S/C22H25ClN2O8/c1-12-8-18-17(33-18)5-3-2-4-13(25-31-11-19(29)24-6-7-26)9-14-20(22(30)32-12)15(27)10-16(28)21(14)23/h2-5,10,12,17-18,26-28H,6-9,11H2,1H3,(H,24,29)/b4-2+,5-3-,25-13+/t12-,17-,18-/m1/s1
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PC sid
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Similars

Article
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of v-Src tyrosine kinase autophosphorylation in SR3Y1 cells after 15 hr exposure


J Med Chem 46: 2534-41 (2003)


Article DOI: 10.1021/jm030110r
BindingDB Entry DOI: 10.7270/Q2H41QTG
More data for this
Ligand-Target Pair