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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase SRC' and Monomerid = 50128848   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase SRC


(Rattus norvegicus)
BDBM50128848
PNG
(2-(16-Chloro-17,19-dihydroxy-4-methyl-2-oxo-3,7-di...)
Show SMILES C[C@@H]1C[C@H]2O[C@@H]2\C=C/C=C/C(/Cc2c(Cl)c(O)cc(O)c2C(=O)O1)=N\OCC(=O)NCCc1cccn1C
Show InChI InChI=1S/C27H30ClN3O7/c1-16-12-23-22(38-23)8-4-3-6-17(13-19-25(27(35)37-16)20(32)14-21(33)26(19)28)30-36-15-24(34)29-10-9-18-7-5-11-31(18)2/h3-8,11,14,16,22-23,32-33H,9-10,12-13,15H2,1-2H3,(H,29,34)/b6-3+,8-4-,30-17+/t16-,22-,23-/m1/s1
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Similars

Article
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of v-Src tyrosine kinase autophosphorylation in SR3Y1 cells after 15 hr exposure


J Med Chem 46: 2534-41 (2003)


Article DOI: 10.1021/jm030110r
BindingDB Entry DOI: 10.7270/Q2H41QTG
More data for this
Ligand-Target Pair