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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase SRC' and Monomerid = 50128852   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase SRC


(Rattus norvegicus)
BDBM50128852
PNG
(2-(16-Chloro-17,19-dihydroxy-4-methyl-2-oxo-3,7-di...)
Show SMILES C[C@@H]1C[C@H]2O[C@@H]2\C=C/C=C/C(/Cc2c(Cl)c(O)cc(O)c2C(=O)O1)=N\OCC(=O)NC1CCCC1
Show InChI InChI=1S/C25H29ClN2O7/c1-14-10-21-20(35-21)9-5-4-8-16(28-33-13-22(31)27-15-6-2-3-7-15)11-17-23(25(32)34-14)18(29)12-19(30)24(17)26/h4-5,8-9,12,14-15,20-21,29-30H,2-3,6-7,10-11,13H2,1H3,(H,27,31)/b8-4+,9-5-,28-16+/t14-,20-,21-/m1/s1
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MMDB

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Similars

Article
PubMed
n/an/a 14n/an/an/an/an/an/a



Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of v-Src tyrosine kinase autophosphorylation in SR3Y1 cells after 15 hr exposure


J Med Chem 46: 2534-41 (2003)


Article DOI: 10.1021/jm030110r
BindingDB Entry DOI: 10.7270/Q2H41QTG
More data for this
Ligand-Target Pair