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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase SRC' and Monomerid = 50128860   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase SRC


(Rattus norvegicus)
BDBM50128860
PNG
(2-(16-Chloro-17,19-dihydroxy-4-methyl-2-oxo-3,7-di...)
Show SMILES COc1ccc(NC(=O)CO\N=C2\Cc3c(Cl)c(O)cc(O)c3C(=O)O[C@H](C)C[C@H]3O[C@@H]3/C=C\C=C\2)cc1
Show InChI InChI=1S/C27H27ClN2O8/c1-15-11-23-22(38-23)6-4-3-5-17(12-19-25(27(34)37-15)20(31)13-21(32)26(19)28)30-36-14-24(33)29-16-7-9-18(35-2)10-8-16/h3-10,13,15,22-23,31-32H,11-12,14H2,1-2H3,(H,29,33)/b5-3+,6-4-,30-17+/t15-,22-,23-/m1/s1
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MMDB

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Similars

Article
PubMed
n/an/a 390n/an/an/an/an/an/a



Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of v-Src tyrosine kinase autophosphorylation in SR3Y1 cells after 15 hr exposure


J Med Chem 46: 2534-41 (2003)


Article DOI: 10.1021/jm030110r
BindingDB Entry DOI: 10.7270/Q2H41QTG
More data for this
Ligand-Target Pair