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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cathepsin L' and Monomerid = 50128951   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cathepsin L1


(Homo sapiens (Human))
BDBM50128951
PNG
(4-Ethyl-N-{(S)-1-[2-(4-methoxy-phenylamino)-ethylc...)
Show SMILES CCc1ccc(cc1)C(=O)N[C@@H](CC(C)C)C(=O)NCCNc1ccc(OC)cc1
Show InChI InChI=1S/C24H33N3O3/c1-5-18-6-8-19(9-7-18)23(28)27-22(16-17(2)3)24(29)26-15-14-25-20-10-12-21(30-4)13-11-20/h6-13,17,22,25H,5,14-16H2,1-4H3,(H,26,29)(H,27,28)/t22-/m0/s1
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Similars

Article
PubMed
n/an/a 30n/an/an/an/an/an/a



Novartis Pharma AG

Curated by ChEMBL


Assay Description
Inhibitory activity against recombinant human cathepsin L activity


Bioorg Med Chem Lett 13: 1997-2001 (2003)


Article DOI: 10.1016/s0960-894x(03)00344-5
BindingDB Entry DOI: 10.7270/Q2VD6XTQ
More data for this
Ligand-Target Pair